Adware Removal in huge environment

I am an security analyst , monitoring proxy logs of my company, I could see lots of unwanted traffic towards adware website. Is there any way which i can use to remove adwares from machine remotely without disturbing the user operation.
The traffic is always not caused by a program, it may be because of a process or service. Now i am using adware cleaner to remove adwares manually. Is there any way to remove them, if the number of systems are huge

Source: virus

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